abstract：CONTEXT:Medical expulsive therapy (MET) for urolithiasis has gained increasing attention in the last years. It has been suggested that the administration of alpha-adrenoreceptor antagonists (alpha-blockers) or calcium channel blockers augments stone expulsion rates and reduces colic events. OBJECTIVE:To evaluate the e...

journal_title：European urology

authors： Seitz C,Liatsikos E,Porpiglia F,Tiselius HG,Zwergel U

更新日期：2009-09-01 00:00:00

abstract：CONTEXT:In 2005, fusions between the androgen-regulated transmembrane protease serine 2 gene, TMPRSS2, and E twenty-six (ETS) transcription factors were discovered in prostate cancer. OBJECTIVE:To review advances in our understanding of ETS gene fusions, focusing on challenges affecting translation to clinical applica...

journal_title：European urology

authors： Tomlins SA,Bjartell A,Chinnaiyan AM,Jenster G,Nam RK,Rubin MA,Schalken JA

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Use of an augmented reality (AR)-based soft tissue navigation system in urologic laparoscopic surgery is an evolving technique. OBJECTIVE:To evaluate a novel soft tissue navigation system developed to enhance the surgeon's perception and to provide decision-making guidance directly before initiation of kidn...

journal_title：European urology

authors： Teber D,Guven S,Simpfendörfer T,Baumhauer M,Güven EO,Yencilek F,Gözen AS,Rassweiler J

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Testosterone (T) induces a rapid relaxation in vascular tissues of different species due to a nongenomic effect of this steroid on vessels. Different mechanisms have been proposed to explain T-induced vasodilatation but the effective mechanism(s) and the mediators involved are still a matter of debate. OBJE...

journal_title：European urology

authors： Bucci M,Mirone V,Di Lorenzo A,Vellecco V,Roviezzo F,Brancaleone V,Ciro I,Cirino G

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Previous studies in humans, dogs, and rats have shown that intraprostatic injection of botulinum neurotoxin type A (BoNTA) reduces gland size. OBJECTIVE:To investigate the role of eventual impairment of sympathetic, parasympathetic, and sensory nerves to gland atrophy after intraprostatic BoNTA administrati...

journal_title：European urology

authors： Silva J,Pinto R,Carvallho T,Coelho A,Avelino A,Dinis P,Cruz F

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Data about the use of tension-free vaginal tape (TVT) in the management of recurrent urodynamic stress incontinence (RUSI) after previous failed midurethral sling procedure (MUSP) are limited. OBJECTIVE:Assessment of the efficacy and the indications of the TVT procedure in the management of patients with RU...

journal_title：European urology

authors： Liapis A,Bakas P,Creatsas G

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The oncologic safety of blunt tumor enucleation (TE) of renal cell carcinoma (RCC) depends on the presence of a continuous pseudocapsule (PS) around the tumor and on the possibility of obtaining negative surgical margins (SMs). OBJECTIVE:To investigate the PS and SMs after TE to define the real need to take...

journal_title：European urology

authors： Minervini A,di Cristofano C,Lapini A,Marchi M,Lanzi F,Giubilei G,Tosi N,Tuccio A,Mancini M,della Rocca C,Serni S,Bevilacqua G,Carini M

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:While the published short-term oncologic outcomes after laparoscopic radical prostatectomy (LRP) are encouraging, intermediate and long-term data are lacking. OBJECTIVE:We analyzed the oncologic outcome after LRP based on 10 yr of experience. DESIGN, SETTING, AND PARTICIPANTS:This retrospective analysis of...

journal_title：European urology

authors： Touijer K,Secin FP,Cronin AM,Katz D,Bianco F,Vora K,Reuter V,Vickers AJ,Guillonneau B

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:The endothelin-A receptor (ETAR) has been implicated in the progression of prostate cancer. OBJECTIVES:To investigate the safety and efficacy of the specific ETAR antagonist ZD4054 in patients with metastatic hormone-resistant prostate cancer (HRPC). DESIGN, SETTING, AND PARTICIPANTS:Double-blind, placebo-...

journal_title：European urology

authors： James ND,Caty A,Borre M,Zonnenberg BA,Beuzeboc P,Morris T,Phung D,Dawson NA

更新日期：2009-05-01 00:00:00

abstract：CONTEXT:Uncertainty remains about the extent and indications for inguinal lymphadenectomy in penile cancer, a procedure known for relatively high morbidity. Several attempts have been made to develop strategies which can improve the diagnostic quality and reduce the morbidity of the management of inguinal lymph nodes i...

journal_title：European urology

authors： Protzel C,Alcaraz A,Horenblas S,Pizzocaro G,Zlotta A,Hakenberg OW

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:A role for the transient receptor potential (TRP) A1 ion channel in rat lower urinary tract (LUT) sensation and disease has been proposed, but in the human LUT no information on TRPA1 activity is available. OBJECTIVES:To investigate the distribution of TRPA1 in the human urethra and to study the effect of T...

journal_title：European urology

authors： Gratzke C,Streng T,Waldkirch E,Sigl K,Stief C,Andersson KE,Hedlund P

更新日期：2009-03-01 00:00:00

abstract：CONTEXT:The use of neoadjuvant and adjuvant chemotherapy in the treatment of muscle-invasive bladder cancer is still controversial. OBJECTIVE:To determine the optimal use of chemotherapy in the neoadjuvant and adjuvant settings in patients with advanced urothelial cell carcinoma. Bladder preservation is also discussed...

journal_title：European urology

authors： Calabrò F,Sternberg CN

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Currently two pretreatment prognostic models with limited accuracy (65-67%) can be used to predict survival in patients with localized renal cell carcinoma (RCC). OBJECTIVE:We set out to develop a more accurate pretreatment model for predicting RCC-specific mortality after nephrectomy for all stages of RCC....

journal_title：European urology

authors： Karakiewicz PI,Suardi N,Capitanio U,Jeldres C,Ficarra V,Cindolo L,de la Taille A,Tostain J,Mulders PF,Bensalah K,Artibani W,Salomon L,Zigeuner R,Valéri A,Descotes JL,Rambeaud JJ,Méjean A,Montorsi F,Bertini R,Patard

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Limited data on patterns of recurrence (local or metastatic) after salvage radical prostatectomy (SP) is available. OBJECTIVE:To examine biochemical, local and metastatic patterns of recurrence in patients undergoing SP for radiation-recurrent prostate cancer. DESIGN, SETTING, AND PARTICIPANTS:146 patients...

journal_title：European urology

authors： Paparel P,Cronin AM,Savage C,Scardino PT,Eastham JA

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Literature regarding both subjective and objective evaluations of erectile function following radical cystectomy is deficient. OBJECTIVE:To study the recoverability of erectile function in post-radical cystectomy patients on subjective and objective bases. DESIGN, SETTING, AND PARTICIPANTS:Between March 20...

journal_title：European urology

authors： Hekal IA,El-Bahnasawy MS,Mosbah A,El-Assmy A,Shaaban A

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Perioperative cisplatin combination chemotherapy is associated with a survival benefit in patients with invasive bladder cancer (BCa). However, in a recent report from the National Cancer Database (NCDB), only 11.6% of stage III BCa patients received perioperative chemotherapy, the majority in the adjuvant s...

journal_title：European urology

authors： Donat SM,Shabsigh A,Savage C,Cronin AM,Bochner BH,Dalbagni G,Herr HW,Milowsky MI

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Conventional gray scale ultrasound has a low sensitivity and specificity for prostate cancer detection. Better imaging modalities are needed. OBJECTIVE:To determine sensitivity and specificity for prostate cancer detection with ultrasound-based real-time elastography (elastography) in patients scheduled for...

journal_title：European urology

authors： Salomon G,Köllerman J,Thederan I,Chun FK,Budäus L,Schlomm T,Isbarn H,Heinzer H,Huland H,Graefen M

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:Outcome data from a prospective study of active surveillance of localised prostate cancer were analysed to identify factors, present at the time of diagnosis, that predict subsequent radical treatment. METHODS:Eligible patients had clinical stage T1-T2a, N0-Nx, M0-Mx adenocarcinoma of the prostate with seru...

journal_title：European urology

authors： van As NJ,Norman AR,Thomas K,Khoo VS,Thompson A,Huddart RA,Horwich A,Dearnaley DP,Parker CC

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:The functional outcome of a nerve-sparing radical prostatectomy (RP) depends on the knowledge of autonomic nerve distribution in correlation to the prostate. OBJECTIVE:Recent literature has focused predominantly on the anterior prostate; this study evaluates the nerve distribution on the entire prostate, us...

journal_title：European urology

authors： Sievert KD,Hennenlotter J,Laible I,Amend B,Schilling D,Anastasiadis A,Kuehs U,Nagele U,Stenzl A

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:To determine the genetic and environmental influence on the liability for stress urinary incontinence and pelvic organ prolapse surgery. METHODS:We used the Swedish Twin Registry to identify all same-sex female twin pairs with known zygosity born from 1926 to 1958. Occurrence of stress urinary incontinence ...

journal_title：European urology

authors： Altman D,Forsman M,Falconer C,Lichtenstein P

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVES:Prostaglandin E2 (PGE2) is a potent immune modulator and known to suppress both tumour antigen-specific helper T (TH1) cells and the generation of cytotoxic T lymphocytes (CTLs). We hypothesised that a combination of the cyclooxygenase 2 (COX-2) selective inhibitor celecoxib and intravesical bacillus Calmett...

journal_title：European urology

authors： Dovedi SJ,Kirby JA,Davies BR,Leung H,Kelly JD

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:The exact distribution of periprostatic autonomic nerves is under debate. OBJECTIVE:To study the topographical anatomy of autonomic nerves of the periprostatic tissue and the capsule of the prostate (CAP). DESIGN, SETTING, AND PARTICIPANTS:Whole-mount sections of 30 prostates from patients having undergone...

journal_title：European urology

authors： Ganzer R,Blana A,Gaumann A,Stolzenburg JU,Rabenalt R,Bach T,Wieland WF,Denzinger S

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:To describe a new surgical technique for the repair of bulbar urethral strictures to preserve the bulbospongiosum muscle and its perineal innervation. OBJECTIVE:Surgical steps of muscle- and nerve-sparing bulbar urethroplasty are described. The outcome is provided regarding semen sequestration and postvoidi...

journal_title：European urology

authors： Barbagli G,De Stefani S,Annino F,De Carne C,Bianchi G

更新日期：2008-08-01 00:00:00

abstract：:The current practice of withdrawing antiplatelet therapy before major surgery has been challenged by the introduction of coronary drug-eluting stents (DESs) since evidence is accumulating that a DES requires dual antiplatelet therapy for at least a year. The authors present a case demonstrating difficulty in decision-...

journal_title：European urology

authors： de Korte FI,van Werkum JW,Vijverberg PL,Ten Berg JM

更新日期：2008-07-01 00:00:00

abstract：CONTEXT AND OBJECTIVES:Interest in laparoscopic assisted radical cystectomy (LRC) and robotic assisted radical cystectomy (RRC) is increasing at select centers worldwide. In this update we present the recent worldwide experience and critically evaluate the role of minimally invasive radical surgery for patients with bl...

journal_title：European urology

authors： Haber GP,Crouzet S,Gill IS

更新日期：2008-07-01 00:00:00

abstract：:This case study reports one case of transvaginal natural orifice transluminal endoscopic surgery (NOTES) in a 23-yr-old woman with right flank pain and recurrent urinary tract infection due to a nonfunctional right kidney. She underwent nephrectomy by transvaginal NOTES using the endoscope by vaginal access and two ad...

journal_title：European urology

authors： Branco AW,Branco Filho AJ,Kondo W,Noda RW,Kawahara N,Camargo AA,Stunitz LC,Valente J,Rangel M

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:Based on our recently published anatomic studies, we present the most recent refinement of the endoscopic extraperitoneal radical prostatectomy (EERPE), the intrafascial nerve-sparing EERPE (nsEERPE). METHODS:As part of the intrafascial technique, the dissection plane is directly on the prostatic capsule, f...

journal_title：European urology

authors： Stolzenburg JU,Rabenalt R,Do M,Schwalenberg T,Winkler M,Dietel A,Liatsikos E

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To investigate the prostate cancer (PCa) prevalence and risk factors of men with prostate-specific antigen (PSA) level< or =4.0 ng/ml and an unsuspicious digital rectal examination (DRE) in a large biopsy referral cohort. MATERIALS AND METHODS:Between 1997 and 2005, 855 men underwent initial transrectal ultr...

journal_title：European urology

authors： Ahyai SA,Graefen M,Steuber T,Haese A,Schlomm T,Walz J,Köllermann J,Briganti A,Zacharias M,Friedrich MG,Karakiewicz PI,Montorsi F,Huland H,Chun FK

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:High-intensity focused ultrasound (HIFU) permits targeted homogeneous ablation of tissue. The objective of this phase 1 study was to evaluate the feasibility of HIFU ablation of small renal tumours under laparoscopic control. PATIENTS AND METHODS:Ten kidneys with solitary renal tumours were treated with a ne...

journal_title：European urology

authors： Klingler HC,Susani M,Seip R,Mauermann J,Sanghvi N,Marberger MJ

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To compare the oncologic outcomes of nephron-sparing surgery versus radical nephrectomy in intracapsular renal cell carcinoma (RCC) up to 7 cm by reviewing surgical experience retrospectively. METHODS:Data from 1290 consecutive patients who had surgery for RCC have been stored in a dedicated database since 1...

journal_title：European urology

authors： Antonelli A,Cozzoli A,Nicolai M,Zani D,Zanotelli T,Perucchini L,Cunico SC,Simeone C

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:To assess if prostate-specific antigen (PSA) nadir is an independent predictor of treatment failure and disease-free survival after high-intensity focussed ultrasound (HIFU) therapy for localised prostate cancer as defined by the new ASTRO criteria. METHODS:One hundred three patients after HIFU treatment (A...

journal_title：European urology

authors： Ganzer R,Rogenhofer S,Walter B,Lunz JC,Schostak M,Wieland WF,Blana A

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:To study the effect of botulinum toxin A (BoNTA) injections into the detrusor muscle on the incidence of symptomatic urinary infections in patients with neurogenic detrusor overactivity. METHODS:Between February 2004 and June 2005, 30 patients (18 men, 12 women), mean age 39.4+/-12.1 yr, with neurogenic det...

journal_title：European urology

authors： Gamé X,Castel-Lacanal E,Bentaleb Y,Thiry-Escudié I,De Boissezon X,Malavaud B,Marque P,Rischmann P

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:Laparoscopic partial nephrectomy requires advanced training to accomplish tumor resection and renal reconstruction while minimizing warm ischemia times. Complex renal tumors add an additional challenge to a minimally invasive approach to nephron-sparing surgery. We describe our technique, illustrated with vi...

journal_title：European urology

authors： Rogers CG,Singh A,Blatt AM,Linehan WM,Pinto PA

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:To review the role of postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) in patients with advanced testicular germ cell tumours (TGCT) with special attention towards the indication, surgical technique, and oncological outcome. METHODS:A structured review of the literature until May 2007 using...

journal_title：European urology

authors： Heidenreich A,Thüer D,Polyakov S

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVES:It is known that African American men have a greater risk of prostate cancer than white men. We investigated whether this was true for first-generation black Caribbean and black African men in the United Kingdom. METHODS:A clinical cohort study design recruiting all cases of prostate cancer diagnosed over a...

journal_title：European urology

authors： Ben-Shlomo Y,Evans S,Ibrahim F,Patel B,Anson K,Chinegwundoh F,Corbishley C,Dorling D,Thomas B,Gillatt D,Kirby R,Muir G,Nargund V,Popert R,Metcalfe C,Persad R,PROCESS study group.

更新日期：2008-01-01 00:00:00

abstract：:We report on the case of a 44-yr-old white man who was referred as an emergency from a local hospital to the medical intensive care unit (ICU) at our institution for progressive multiorgan failure of unknown cause. The CT scan of the abdomen showed a horseshoe kidney with extensive stone formation in both kidneys and ...

journal_title：European urology

authors： Pühse G,Piechota H,Scheffold C,Kloska S,Hertle L,Wülfing C

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:In patients with prostate cancer, extended pelvic lymph node dissection (ePLND) yields a higher number of lymph node metastases (LNM) than standard pelvic lymph node dissection (PLND) of the obturator fossa only. We describe our laparoscopic technique of extended lymph node dissection and provide the number a...

journal_title：European urology

authors： Lattouf JB,Beri A,Jeschke S,Sega W,Leeb K,Janetschek G

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:To assess the usefulness of the phosphodiesterase type 5 inhibitors (PDE5-Is) in the treatment of premature ejaculation (PE) and to describe possible mechanisms to explain their effect. METHODS:A MedLine search was performed for peer-reviewed articles on the role of PDE5-Is in managing PE. No meta-analysis ...

journal_title：European urology

authors： Chen J,Keren-Paz G,Bar-Yosef Y,Matzkin H

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:TIMPs control the activity of MMPs, one of the key molecules for tumor invasion and metastasis. The aim of this study was to assess the usefulness of MMP-2 and MMP-9 in relation to their inhibitor (TIMP2) as noninvasive diagnostic tests for bilharzial bladder cancer. MATERIAL AND METHODS:Voided urine sample...

journal_title：European urology

authors： Eissa S,Ali-Labib R,Swellam M,Bassiony M,Tash F,El-Zayat TM

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:We evaluated the reliability of sonographic criteria in selecting solid renal masses for percutaneous fine-needle biopsy. METHODS:In study 1 (intraoperative ultrasound study), we prospectively examined 100 consecutive patients scheduled for partial/radical nephrectomy by using two different high-resolution ...

journal_title：European urology

authors： Reichelt O,Gajda M,Chyhrai A,Wunderlich H,Junker K,Schubert J

更新日期：2007-11-01 00:00:00